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Symbol
Name
ID
Piezo1
piezo-type mechanosensitive ion channel component 1
MGI:3603204
Phenotype annotations related to cardiovascular system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Splenomegaly
Disease(s) Associated with PIEZO1
dehydrated hereditary stomatocytosis 1

Mouse Phenotypes
cardiovascular system phenotype
abnormal vascular endothelial cell morphology
abnormal intersomitic vessel morphology
abnormal developmental vascular remodeling
absent organized vascular network
abnormal vitelline vasculature morphology
disorganized yolk sac vascular plexus
pericardial effusion
abnormal vascular endothelial cell physiology
Availability Mouse Genotype
Piezo1Gt(RST343)Byg/Piezo1Gt(RST343)Byg *
Piezo1tm1a(KOMP)Wtsi/Piezo1tm1a(KOMP)Wtsi
Piezo1tm1a(KOMP)Wtsi/Piezo1+
Piezo1tm1c(KOMP)Wtsi/Piezo1tm1c(KOMP)Wtsi
Tg(Tek-cre)12Flv/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory